The verse goes:
Maybe I’m just Cassandra fleeting
Twentieth Century icon bleeding
Willing to risk salvation
To escape from isolation
Cassandra was a figure in Greek mythology who was the object of the god Apollo’s affections. He gave her the power to tell the future, but when she would not return his love, he made it so that no one would ever believe the prophecies she gave, although they were right.
She foretold the downfall of the city of Troy, but no one she told would believe her. So she knew it was going to happen, but couldn’t warn anyone.
Petrucci wrote Voices about mental illnes, particularly schizophrenia, while using religious themes to make the song more metaphorical and vivid. “…There was a guy who felt that his skin was inside out.” Petrucci said. “I read that and was like ‘Oh my God! That’s unbelievable; I’ve got to write about that.”